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Sarpogrelate hydrochloride

Cat. No.：135159-51-2

  • CAS No. ：135159-51-2

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    • 产品名称: Sarpogrelate hydrochloride
      CAS No.: 135159-51-2
      Chemical Name:
      Synonyms:盐酸沙格雷酯; MCI-9042
      分子量:465.97
      分子式:C₂₄H₃₂ClNO₆
      SMILES:COC1=CC=CC(CCC2=CC=CC=C2OCC(CN(C)C)OC(CCC(O)=O)=O)=C1.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Rashid, M., Manivet, P., Nishio, H., et al.Identification of the binding sites and selectivity of sarpogrelate, a novel 5-HT2 antagonist, to human 5-HT2A, 5-HT2B and 5-HT2C receptor subtypes by molecular modelingLife Sci.73(2),193-207(2003)', 'Maruyama, K., Kinami, J., Sugita, Y., et al.MCI-9042: High affinity for serotonergic receptors as assessed by radioligand binding assayJ. Pharmacobiodyn.14(4),177-181(1991)', 'Kubacka, M., Kazek, G., Kotańska, M., et al.Anti-aggregation effect of aroxyalkyl derivatives of 2-methoxyphenylpiperazine is due to their 5-HT2A and α2-adrenoceptor antagonistic properties. A comparison with ketanserin, sarpogrelate, prazosin, yohimbine and ARC239Eur. J. Pharmacol.818,263-270(2018)', 'Kataoka, H., Ariyama, Y., Deushi, M., et al.Inhibitory effect of serotonin antagonist on leukocyte-endothelial interactions in vivo and in vitroPLoS One11(1),e0147929(2016)', 'Brasil, D., Temsah, R.M., Kumar, K., et al.Blockade of 5-HT2A receptors by sarpogrelate protects the heart against myocardial infarction in ratsJ. Cardiovasc. Pharmacol. Ther.7(1),53-59(2002)
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