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Volinanserin

Cat. No.：139290-65-6

  • CAS No. ：139290-65-6

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    • 产品名称: Volinanserin
      CAS No.: 139290-65-6
      Chemical Name:
      Synonyms:MDL100907; M 100907
      分子量:373.46
      分子式:C₂₂H₂₈FNO₃
      SMILES:FC1=CC=C(CCN2CCC([C@@]([H])(O)C3=CC=CC(OC)=C3OC)CC2)C=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Sorensen, S.M., Kehne, J.H., Fadayel, G.M., et al.Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: Behavioral, electrophysiological and neurochemical studiesJ. Pharmacol. Exp. Ther.266(2),684-691(1993)', 'Kehne, J.H., Baron, B.M., Carr, A.A., et al.Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profileJ. Pharmacol. Exp. Ther.277(2),968-981(1996)', 'Pehek, E.A., Nocjar, C., Roth, B.L., et al.Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortexNeuropsychopharmacology31(2),265-277(2006)', 'Ardayfio, P.A., Benvenga, M.J., Chaney, S.F., et al.The 5-hydroxytryptamine2A receptor antagonist R-(+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-4-piperidinemethanol (M100907) attenuates impulsivity after both drug-induced disruption (dizocilpine) and enhancement (antidepressant drugs) of differential-reinforcement-of-low-rate 72-s behavior in the ratJ. Pharmacol. Exp. Ther.327(3),891-897(2008)', 'Boothman, L.J., Mitchell, S.N., and Sharp, T.Investigation of the SSRI augmentation properties of 5-HT2 receptor antagonists using in vivo microdialysisNeuropharmacology50(6),726-732(2006)
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