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RS-127445 hydrochloride

Cat. No.：199864-86-3

  • CAS No. ：199864-86-3

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    • 产品名称: RS-127445 hydrochloride
      CAS No.: 199864-86-3
      Chemical Name:
      Synonyms:4-(4-氟-1-萘基)-6-(1-甲基乙基)-2-嘧啶胺盐酸盐,RS 127445,MT 500
      分子量:317.79
      分子式:C₁₇H₁₇ClFN₃
      SMILES:NC1=NC(C(C)C)=CC(C2=C3C=CC=CC3=C(F)C=C2)=N1.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Bonhaus, D.W., Flippin, L.A., Greenhouse, R.J., et al.RS-127445: A selective, high affinity, orally bioavailable 5-HT2B receptor antagonistBr. J. Pharmacol.127(5),1075-1082(1999)', 'Bassil, A.K., Taylor, C.M., Bolton, V.J., et al.Inhibition of colonic motility and defecation by RS-127445 suggests an involvement of the 5-HT2B receptor in rodent large bowel physiologyBr. J. Pharmacol.158(1),252-258(2009)', 'Devroye, C., Cathala, A., Di Marco, B., et al.Central serotonin2B receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflowNeuropharmacology97,329-337(2015)
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