JP1302 dihydrochloride
Cat. No.：YN320249
CAS No. ：1259314-65-2
| 产品名称: | JP1302 dihydrochloride |
| CAS No.: | 1259314-65-2 |
| Chemical Name: | N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinamine Dihydrochloride; N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinamine Hydrochloride (1:2) |
| Synonyms: | |
| 分子量: | 441.40 |
| 分子式: | C₂₄H₂₆Cl₂N₄ |
| SMILES: | CN1CCN(C2=CC=C(NC3=C(C=CC=C4)C4=NC5=CC=CC=C53)C=C2)CC1.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JP1302 dihydrochloride 是选择性的、高亲和力的α2C肾上腺受体 (α2C-adrenoceptor)的拮抗剂，其Kb值为 16 nM，Ki值为 28 nM。 |
| IC50和靶点: | [{name:"human α2C-adrenoceptor:28±2 nM (Ki)"},{name: "human α2B-adrenoceptor:1470±130 nM (Ki)"},{name: "human α2A-adrenoceptor:3150±50 nM (Ki)"},{name: "rodent α2D-adrenoceptor:1700±200 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tsutsui, H.
Yukimura, T.: PCT Int. Appl. 23pp. Patent 2013 CODEN:PIXXD2
