ULS 欢迎您!
ULS 欢迎您!
> 产品中心 > 抑制剂 & 激动剂 > Neuronal Signaling > Adrenergic Receptor

(S)-Timolol Maleate

Cat. No.:YN321126

  • CAS No. :26921-17-5

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: (S)-Timolol Maleate
      CAS No.: 26921-17-5
      Chemical Name: (2S)-1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol, 2Z-butenedioate
      Synonyms:(S)-马来酸噻吗洛尔; L-714,465 Maleate; MK 950
      分子量:432.49
      分子式:C₁₇H₂₈N₄O₇S
      SMILES:O[C@H](COC1=NSN=C1N2CCOCC2)CNC(C)(C)C.O=C(O)/C=C\C(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: (S)-Timolol Maleate (L-714,465 Maleate) 是一种非心脏选择性的亲水性 β-肾上腺素受体 (β-adrenoceptor) 阻滞剂。(S)-Timolol Maleate 通过防止房水的产生而被广泛用作眼压(青光眼)的标准药物。(S)-Timolol Maleate 可用于高血压,心绞痛和心肌梗塞的研究。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Baker, J.G.The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptorsBr. J. Pharmacol.144(3),317-322(2005)

      Tosi, G., Zironi, F., Caselli, E., et al.Biocatalytic asymmetric synthesis of 9S)- and (R)-timololSynthesis10,1625-1628(2004)

      Mehvar, R., and Brocks, D.R.Stereospecific pharmacokinetics and pharmacodynamics of β-adrenergic blockers in humansJ. Pharm. Pharm. Sci.4(2),185-200(2001)

      Cheng, J.W., Cheng, S.W., Gao, L.D., et al.Intraocular pressure-lowering effects of commonly used fixed-combination drugs with Timolol: A systematic review and meta-analysisPLoS One7(9),45079(2012)

      Li, N., Chen, X.m., Zhou, Y., et al.Travoprost compared with other prostaglandin analogues or timolol in patients with open-angle glaucoma or ocular hypertension: Meta-analysis of randomized controlled trialsClin. Exp. Ophthalmol.34(8),755-764(2006)

    • 摩尔计算器
    • 稀释计算器
    摩尔浓度计算器方程 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    计算

    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
    • C1
      V1
      C2
      V2
    • 您最近查看的产品:
    相关产品


    ULS 的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务(也不为任何个人提供产品和服务)Copyright © 2020-2021 ULS. All Rights Reserved. 备案号:粤ICP备2021013238号-1
    0.360475s