Carteolol hydrochloride
Cat. No.：YN321147
CAS No. ：51781-21-6
| 产品名称: | Carteolol hydrochloride |
| CAS No.: | 51781-21-6 |
| Chemical Name: | 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone, monohydrochloride |
| Synonyms: | 盐酸卡替洛尔; OPC-1085 hydrochloride |
| 分子量: | 328.83 |
| 分子式: | C₁₆H₂₅ClN₂O₃ |
| SMILES: | O=C1NC2=C(C(OCC(O)CNC(C)(C)C)=CC=C2)CC1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Carteolol hydrochloride (OPC-1085 hydrochloride) 是非选择性β肾上腺素受体阻断剂。 |
| IC50和靶点: | |
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Takayanagi, I., Ogishima, M., Koike, K., et al.Dose difference in beta-adrenergic blockers with intrinsic sympathomimetic action to block beta-adrenoceptors and induce sympathomimetic actionGen. Pharmacol.20(4),417-419(1989)
Gwathmey, J.K., Kim, C.S., Haijar, R.J., et al.Cellular and molecular remodeling in a heart failure model treated with the β-blocker carteololAm. J. Physiol.276(5 Pt. 2),H1678-H1690(1999)
Yabuochi, Y., and Kinoshita, D.Cardiovascular studies of 5-(3-tert-butylamino-2-hydroxy) propoxy-3,4-dihydrocarbostyril hydrochloride (OPC-1085), a new potent β-adrenergic blocking agentJpn. J. Pharmacol.24(6),853-861(1974)
Takayanagi, I., Haiwara, H., Koike, K., et al.Effects of the R(+)- and S(-)-isomers of β-adrenoceptor blockers with intrinsic sympathomimetic activity, befunolol and carteolol, on rabbit intraocular pressureCan. J. Physiol. Pharmacol.69(8),1243-1245(1991)
