Naftopidil
Cat. No.：YN321479
CAS No. ：57149-07-2
| 产品名称: | Naftopidil |
| CAS No.: | 57149-07-2 |
| Chemical Name: | 4-(2-Methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-1-piperazineethanol; Naftopil; (+/-)-Naftopidil; |
| Synonyms: | 萘哌地尔; KT-611; BM-15275 |
| 分子量: | 392.49 |
| 分子式: | C₂₄H₂₈N₂O₃ |
| SMILES: | OC(CN1CCN(C(C=CC=C2)=C2OC)CC1)COC3=CC=CC4=CC=CC=C34 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Naftopidil (KT-611) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，具有抗增殖作用。Naftopidil 可用于前列腺增生的研究。 |
| IC50和靶点: | [{name:"Alpha-1A adrenergic receptor:3.7 nM (Ki)"},{name: "Alpha-1B adrenergic receptor:20 nM (Ki)"},{name: "Alpha-1D adrenergic receptor:1.2 nM (Ki)"}] |
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| Solvent & Solubility: |
Kirsten, et al.: Eur. J. Clin. Pharmacol., 46, 271 (1994), Farthing, M.J.G., et al.: Postgrad. Med. J., 70, 363 (1994),
