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Sotalol hydrochloride

Cat. No.:YN321498

  • CAS No. :959-24-0

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    • 产品名称: Sotalol hydrochloride
      CAS No.: 959-24-0
      Chemical Name: N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-methanesulfonamide, monohydrochloride
      Synonyms:盐酸索他洛尔; MJ 1999
      分子量:308.82
      分子式:C₁₂H₂₁ClN₂O₃S
      SMILES:OC(C1=CC=C(NS(C)(=O)=O)C=C1)CNC(C)C.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Sotalol hydrochloride (MJ 1999) 是一种非选择性竞争性β-肾上腺素能受体拮抗剂,它还通过抑制钾通道而表现出 III 类抗心律不齐的特性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Antonaccio, M.J., and Gomoll, A.Pharmacology, pharmacodynamics and pharmacokinetics of sotalolAm. J. Cardiol.65(2),12A-21A(1990)

      Tsuchihashi, H., Nakashima, Y., Kinami, J., et al.Characteristics of 125I-iodocyanopindolol binding to β-adrenergic and serotonin-1B receptors of rat brain: Selectivity of β-adrenergic agentsJpn. J. Pharmacol.52(2),195-200(1990)

      Baker, J.G.The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptorsBr. J. Pharmacol.144(3),317-322(2005)

      Agency, W.A.-D.2014 Anti-doping testing figures report,(2014)

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