Sotalol D6 hydrochloride
Cat. No.：YN321499
CAS No. ：1246820-85-8
| 产品名称: | Sotalol D6 hydrochloride |
| CAS No.: | 1246820-85-8 |
| Chemical Name: | N-(4-(1-hydroxy-2-((propan-2-yl-1,1,1,3,3,3-d6)amino)ethyl)phenyl)methanesulfonamide, monohydrochloride |
| Synonyms: | Sotalol D6 hydrochloride |
| 分子量: | 314.86 |
| 分子式: | C₁₂H₁₅D₆ClN₂O₃S |
| SMILES: | OC(C1=CC=C(NS(C)(=O)=O)C=C1)CNC(C([2H])([2H])[2H])C([2H])([2H])[2H].[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sotalol D6 hydrochloride 是 Sotalol hydrochloride 的氘代物。Sotalol hydrochloride 是一种非选择性竞争性 β-肾上腺素能受体拮抗剂，它还通过抑制钾通道而表现出 III 类抗心律不齐的特性。 |
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Lis, R., Morgan, T.K., Jr., Marisca, A.J., et al.Synthesis of novel (aryloxy) propanolamines and related compounds possessing both class II and class III antiarrhythmic activityJ. Med. Chem33(10),2883-2891(1990)
Antonaccio, M.J., and Gomoll, A.Pharmacology, pharmacodynamics and pharmacokinetics of sotalolAm. J. Cardiol.65(2),12A-21A(1990)
Komeichi, K., Tohse, N., Nakaya, H., et al.Effects of N-acetylprocainamide and sotalol on ion currents in isolated guinea-pig ventricular myocytesEur. J. Pharm.187(3),313-322(1990)
