Phenylephrine hydrochloride
Cat. No.：YN321512
CAS No. ：61-76-7
| 产品名称: | Phenylephrine hydrochloride |
| CAS No.: | 61-76-7 |
| Chemical Name: | 3-hydroxy-α-[(methylamino)methyl]-benzenemethanol, monohydrochloride |
| Synonyms: | 盐酸去氧肾上腺素; (R)-(-) |
| 分子量: | 203.67 |
| 分子式: | C₉H₁₄ClNO₂ |
| SMILES: | OC1=CC([C@@H](O)CNC)=CC=C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (R)-(-)-Phenylephrine hydrochloride是一种选择性的α1-肾上腺素能受体激动剂，对α1D，α1B和α1A受体的pKis分为5.86，4.87和4.70。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
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Besse, J.C., and Furchgott, R.F.Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aortaJ. Pharmacol. Exp. Ther.197(1),66-78(1976)
Dogan, M., Peker, R.O., Donmez, S., et al.Magnesium and diltiazem relaxes phenylephrine-precontracted rat aortic ringsInteract. Cardiovasc. Thorac. Surg.15(1),1-4(2012)
Brunsden, A.M., Brookes, S.J.H., Bardhan, K.D., et al.Mechanisms underlying mechanosensitivity of mesenteric afferent fibers to vascular flowAm. J. Physiol. Gastrointest. Liver Physiol.293(2),G422-G428(2007)
