(S)-(-)-Propranolol hydrochloride
Cat. No.：YN321538
CAS No. ：4199-10-4
| 产品名称: | (S)-(-)-Propranolol hydrochloride |
| CAS No.: | 4199-10-4 |
| Chemical Name: | 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-2S-propanol, monohydrochloride |
| Synonyms: | Hemangeol, Inderal |
| 分子量: | 295.80 |
| 分子式: | C₁₆H₂₂ClNO₂ |
| SMILES: | O[C@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (S)-(-)-Propranolol hydrochloride 是一种肾上腺素能受体 (β-adrenergic receptor) 拮抗剂，针对 β1，β2，和β3的 log Kd值分别为 -8.16，-9.08 和 -6.93。(S)-(-)-Propranolol hydrochloride 可以用于高血压，嗜铬细胞瘤，心肌梗塞，心律不齐，心绞痛和肥大心肌病的相关研究。 |
| IC50和靶点: | |
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Baker, J.G.The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptorsBr. J. Pharmacol.144(3),317-322(2005)
Mehvar, R., and Brocks, D.R.Stereospecific pharmacokinetics and pharmacodynamics of β-adrenergic blockers in humansJ. Pharm. Pharm. Sci.4(2),185-200(2001)
Costain, D.W., and Green, A.R.β-Adrenoceptor antagonists inhibit the behavioural responses of rats to increased brain 5-hydroxytryptamineBr. J. Pharmacol.64(2),193-200(1978)
Gerber, J.G., Freed, C.R., and Nies, A.S.Antihypertensive pharmacologyWest. J. Med.132(5),430-439(1980)
