Phenylephrine
Cat. No.：YN321575
| 产品名称: | Phenylephrine |
| CAS No.: | 59-42-7 |
| Chemical Name: | 3-hydroxy-αR-[(methylamino)methyl]-benzenemethanol |
| Synonyms: | 去氧肾上腺素; (R)-(-) |
| 分子量: | 167.21 |
| 分子式: | C₉H₁₃NO₂ |
| SMILES: | O[C@H](C1=CC(O)=CC=C1)CNC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (R)-(-)-Phenylephrine是选择性的α1-肾上腺素受体激动剂，主要用作减充血剂。 |
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Lomasney, J.W., Cotecchia, S., Lorenz, W., et al.Molecular cloning and expression of the cDNA for the α1A-adrenergic receptor. The gene for which is located on human chromosome 5J. Biol. Chem.266(10),6365-6369(1991)
Besse, J.C., and Furchgott, R.F.Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aortaJ. Pharmacol. Exp. Ther.197(1),66-78(1976)
Dogan, M., Peker, R.O., Donmez, S., et al.Magnesium and diltiazem relaxes phenylephrine-precontracted rat aortic ringsInteract. Cardiovasc. Thorac. Surg.15(1),1-4(2012)
Brunsden, A.M., Brookes, S.J.H., Bardhan, K.D., et al.Mechanisms underlying mechanosensitivity of mesenteric afferent fibers to vascular flowAm. J. Physiol. Gastrointest. Liver Physiol.293(2),G422-G428(2007)
Hatton, R.C., Winterstein, A.G., McKelvey, R.P., et al.Efficacy and safety of oral phenylephrine: Systematic review and meta-analysisAnn. Pharmacother.41(3),381-390(2007)
