Todralazine hydrochloride
Cat. No.：YN321597
CAS No. ：3778-76-5
规格
价格(RMB)
库存
| 产品名称: | Todralazine hydrochloride |
| CAS No.: | 3778-76-5 |
| Chemical Name: | 2-(1-phthalazinyl)-hydrazinecarboxylic acid, ethyl ester, monohydrochloride |
| Synonyms: | Ecarazine hydrochloride |
| 分子量: | 268.70 |
| 分子式: | C₁₁H₁₃ClN₄O₂ |
| SMILES: | O=C(NNC1=NN=CC2=C1C=CC=C2)OCC.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Todralazine hydrochloride (Ecarazine hydrochloride) 是一种抗高血压剂，为 β2肾上腺素能受体 (β2AR) 阻滞剂，具有抗氧化、清除自由基的活性。 |
| IC50和靶点: | |
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Falase, A.O., and Salako, L.A.β-Adrenoceptor blockers in the treatment of hypertensionAfr. J. Med. Med. Sci.8(1-2),13-18(1979)
Dimri, M., Joshi, J., Chakrabarti, R., et al.Todralazine protects zebrafish from lethal effects of ionizing radiation: Role of hematopoietic cell expansionZebrafish12(1),33-47(2015)
Murata, K., Hamada, M., Sugimoto, K., et al.A novel mechanism for drug-induced liver failure: Inhibition of histone acetylation by hydralazine derivativesJ. Hepatol.46(2),322-329(2007)
