Penbutolol sulfate
Cat. No.：YN321619
CAS No. ：38363-32-5
| 产品名称: | Penbutolol sulfate |
| CAS No.: | 38363-32-5 |
| Chemical Name: | (2S)-1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol, hemisulfate |
| Synonyms: | (-)-Terbuclomine |
| 分子量: | 340.47 |
| 分子式: | C₁₈H₂₉NO₂ . ₁/₂ H₂O₄S |
| SMILES: | O[C@@H](CNC(C)(C)C)COC1=CC=CC=C1C2CCCC2.[0.5H2SO4] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Penbutolol sulfate ((-)-Terbuclomine) 能够结合β-1肾上腺素能受体和β-2肾上腺素能受体 (两种亚型), 从而使其成为一个非选择性的β阻滞剂, Penbutolol是拟交感神经药, 可用于研究高血压。 |
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Sánchez, C., Arnt, J., and Moltzen, E.K.The antiaggressive potency of (–)-penbutolol involves both 5-HT1A and 5-HT1B receptors and β-adrenoceptorsEur. J. Pharmacol.297(1-2),1-8(1996)
Krawietz, W., Poppert, D., Erdmann, E., et al.β-adrenergic receptors in guinea-pig myocardial tissueNaunyn Schmiedebergs Arch. Pharmacol.295(3),215-224(1976)
Kaiser, J., Härtfelder, G., Lindner, E., et al.Pharmacology of the β-receptor blocker penbutololArzneimittelforschung30(3),420-427(1980)
