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Isoxsuprine hydrochloride

Cat. No.:YN321635

  • CAS No. :579-56-6

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    • 产品名称: Isoxsuprine hydrochloride
      CAS No.: 579-56-6
      Chemical Name: 4-hydroxy-α-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-benzenemethanol, monohydrochloride
      Synonyms:Isolait,Duvadilan,盐酸异克舒令,盐酸苯氧丙酚胺
      分子量:337.84
      分子式:C₁₈H₂₄ClNO₃
      SMILES:OC(C(NC(C)COC1=CC=CC=C1)C)C2=CC=C(O)C=C2.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Isoxsuprine hydrochloride 是 β 肾上腺素受体激动剂,对于子宫肌层和胎盘的 β 肾上腺素受体的Ki值分别为 13.65 μM 和 3.48 μM。Isoxsuprine hydrochloride 也是一种NMDA受体拮抗剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Cook, P., and James, I.Cerebral vasodilators (second of two parts)N. Engl. J. Med.305(26),1560-1564(1981)

      Belloli, C., Carcano, R., Arioli, F., et al.Affinity of isoxsuprine for adrenoreceptors in equine digital artery and implications for vasodilatory actionEquine Vet. J.32(2),119-124(2000)

      Ekert, R.S., and Macallister, C.G.Isoxsuprine hydrochloride in the horse: A reviewJ. Vet. Pharmacol. Ther.25(2),81-87(2002)

      Bentley, G.A., and Starr, J.The antinociceptive action of some β-adrenoceptor agonists in miceBr. J. Pharmacol.88(3),515-521(1988)

      Viswanathan, C.L., Kodgule, M.M., and Chaudhari, A.S.Design, synthesis and evaluation of racemic 1-(4-hydroxyphenyl)-2-[3-(substituted phenoxy)-2-hydroxy-1-propyl]amino-1-propanol hydrochlorides as novel uterine relaxantsBioorg. Med. Chem. Lett.15(15),3532-3535(2005)

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