AZ-23
Cat. No.：YN380112
CAS No. ：915720-21-7
| 产品名称: | AZ-23 |
| CAS No.: | 915720-21-7 |
| Chemical Name: | AZ-23 |
| Synonyms: | AZ23; AZ 23 |
| 分子量: | 391.83 |
| 分子式: | C₁₇H₁₉ClFN₇O |
| SMILES: | CC(OC1=CC(NC2=NC(N[C@H](C3=NC=C(F)C=C3)C)=NC=C2Cl)=NN1)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AZ-23是ATP-竞争型，有口服活性的Trk激酶 A/B/C抑制剂，IC50值分别为2 nM (TrkA)，8 nM (TrkB)，24 nM (FGFR1)，52 nM (Flt3)，55 nM (Ret)，84 nM (MuSk)，99 nM (Lck)。 |
| IC50和靶点: | [{name:"TrkA:2 nM (IC50)"},{name: "TrkB:8 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Thress, L. et al.: Mol. Canc. Ther., 8, 1818 (2009)
