Edonerpic maleate
Cat. No.：YN380127
CAS No. ：519187-97-4
| 产品名称: | Edonerpic maleate |
| CAS No.: | 519187-97-4 |
| Chemical Name: | 1-[3-(2-benzo[b]thien-5-ylethoxy)propyl]-3-azetidinol, 2Z-butenedioate |
| Synonyms: | T-817 maleate; T-817MA |
| 分子量: | 407.48 |
| 分子式: | C₂₀H₂₅NO₆S |
| SMILES: | OC1CN(CCCOCCC2=CC=C3C(C=CS3)=C2)C1.O=C(O)/C=C\C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Edonerpic maleate 是一种新的神经营养剂，其可以抑制淀粉样蛋白 β 肽 (Aβ)。 |
| IC50和靶点: | |
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Fukushima, T., Koide, M., Ago, Y., et al.T-817MA, a novel neurotrophic agent, improves sodium nitroprusside-induced mitochondrial dysfunction in cortical neuronsNeurochem. Int.48(2),124-130(2006)
Nguyen, P.T., Kimura, T., Ho, S.A., et al.Ameliorative effects of a neuroprotective agent, T-817MA, on place learning deficits induced by continuous infusion of amyloid-beta peptide (1-40) in ratsHippocampus17(6),443-455(2007)
Kimura, T., Nguyen, P.T.H., Ho, S.A., et al.T-817MA, a neurotrophic agent, ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-β peptideBr. J. Pharmacol.157(3),451-463(2009)
