Anidulafungin
Cat. No.：YN250491
| 产品名称: | Anidulafungin |
| CAS No.: | 166663-25-8 |
| Chemical Name: | 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B |
| Synonyms: | 阿尼芬净; LY303366 |
| 分子量: | 1140.24 |
| 分子式: | C₅₈H₇₃N₇O₁₇ |
| SMILES: | O[C@@H]1C[C@H](N2C1)C(N[C@@H]([C@H](O)[C@@H](O)C3=CC=C(O)C=C3)C(N[C@@H]([C@@H](C)O)C(N4[C@@H]([C@@H](O)[C@@H](C)C4)C(N[C@H](O)[C@H](O)C[C@H](NC(C5=CC=C(C6=CC=C(C7=CC=C(OCCCCC)C=C7)C=C6)C=C5)=O)C(N[C@@H]([C@H](O)C)C2=O)=O)=O)=O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Anidulafungin 是一种新型的半合成棘球白素，具有抗真菌 (antifungal) 效力。 |
| IC50和靶点: | |
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Vazquez, J.A., and Sobel, J.D.Anidulafungin: A novel echinocandinClin. Infect. Dis.43(2),215-222(2006)
Garcia-Effron, G., Park, S., and Perlin, D.S.Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: Implications for interpretive breakpointsAntimicrob Agents Chemother.53(1),112-122(2009)
Petraitis, V., Petraitiene, R., Groll, A.H., et al.Antifungal efficacy, safety, and single-dose pharmacokinetics of LY303366, a novel echinocandin B, in experimental pulmonary aspergillosis in persistently neutropenic rabbitsAntimicrob Agents Chemother.42(11),2898-2905(1998)
