Etoposide
Cat. No.：YN250522
CAS No. ：33419-42-0
| 产品名称: | Etoposide |
| CAS No.: | 33419-42-0 |
| Chemical Name: | (5aR)-9S-[[4,6-O-ethylidene-β-D-glucopyranosyl]oxy]-5R,8,8aR,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1R,3-dioxol-6(5aH)-one |
| Synonyms: | 依托泊苷; VP-16; VP-16-213 |
| 分子量: | 588.56 |
| 分子式: | C₂₉H₃₂O₁₃ |
| SMILES: | O=C1OC[C@]2([H])[C@H](O[C@H]3[C@@H]([C@H]([C@@H]4O[C@H](C)OC[C@H]4O3)O)O)C5=C(C=C6OCOC6=C5)[C@@H](C7=CC(OC)=C(O)C(OC)=C7)[C@]21[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Etoposide (VP-16; VP-16-213) 是一种常用的抗肿瘤化疗剂。Etoposide 抑制拓扑异构酶 II (topoisomerase-II)，从而抑制 DNA 复制。Etoposide 诱导细胞周期停滞，凋亡 (apoptosis) 和自噬 (autophagy)。 |
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O'Malley, B.Luminescence-based cell-based high throughput dose response assay for inhibitors of the Steroid Receptor Coactivator 3 (SRC;NCOA3) - BioAssay summary,()
