4-Epitetracycline hydrochloride
Cat. No.：YN250538
| 产品名称: | 4-Epitetracycline hydrochloride |
| CAS No.: | 23313-80-6 |
| Chemical Name: | (4R,4aS,5aS,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride |
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| 分子量: | 480.90 |
| 分子式: | C₂₂H₂₅ClN₂O₈ |
| SMILES: | O[C@@]1(C2=O)[C@@]([C@H](C(O)=C2C(N)=O)N(C)C)([H])C[C@@]([C@](O)(C3=CC=CC(O)=C43)C)([H])C(C4=O)=C1O.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4-Epitetracycline hydrochloride is an epimer of the antibiotic tetracycline. Epimers of tetracycline form without catalysis and are considered degradation products. 4-Epitetracycline hydrochloride has decreased activity as an antibiotic or a Tet repressor |
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Degenkolb, J., Takahashi, M., Ellestad, G.A., et al.Structural requirements of tetracycline-Tet repressor interaction: Determination of equilibrium binding constants for tetracycline analogs with the Tet repressorAntimicrob. Agents Chemother.35(8),1591-1595(1991)
Tong, X., Mao, M., Xie, J., et al.Insights into the interactions between tetracycline, its degradation products and bovine serum albuminSpringerPlus5(1),1073(2016)
