Sulfasalazine
Cat. No.：YN250592
| 产品名称: | Sulfasalazine |
| CAS No.: | 599-79-1 |
| Chemical Name: | 2-hydroxy-5-[2-[4-[(2-pyridinylamino)sulfonyl]phenyl]diazenyl]-benzoic acid |
| Synonyms: | 柳氮磺吡啶; NSC 667219 |
| 分子量: | 398.39 |
| 分子式: | C₁₈H₁₄N₄O₅S |
| SMILES: | OC(C1=C(O)C=CC(/N=N/C2=CC=C(S(=O)(NC3=NC=CC=C3)=O)C=C2)=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sulfasalazine (NSC 667219)常用于类风湿关节炎和溃疡性结肠炎的相关演技。Sulfasalazine可抑制NF-κB的活性。 |
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Jiang, G.L., Im, W.B., Donde, Y., et al.Comparison of prostaglandin E2 receptor subtype 4 agonist and sulfasalazine in mouse colitis prevention and treatmentJ. Pharmacol. Exp. Ther.335(3),546-552(2010)
Wahl, C., Liptay, S., Adler, G., et al.Sulfasalazine: a Potent and Specific Inhibitor of Nuclear Factor Kappa BJ. Clin. Invest.101 number 5,1163-1174(1997)
Chung, W.J., and Sontheimer, H.Sulfasalazine inhibits the growth of primary brain tumors independent of nuclear factor-κBJ. Neurochem.110(1),182-193(2009)
Crossley, M.J., Spowage, M., and Hunneyball, I.M.Studies on the effects of pharmacological agents on antigen-induced arthritis in BALB/c miceDrugs Exp. Clin. Res.13(5),273-277(1987)
