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Micafungin sodium

Cat. No.:YN250661

  • CAS No. :208538-73-2

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    • 参考文献
    • 产品名称: Micafungin sodium
      CAS No.: 208538-73-2
      Chemical Name: 1-[(4R,5R)-4,5-dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-pneumocandin A0, monosodium salt
      Synonyms:米卡芬净钠; FK 463 sodium
      分子量:1292.26
      分子式:C₅₆H₇₀N₉NaO₂₃S
      SMILES:O=S(OC1=CC([C@H](O)[C@@H](O)C(NC(C2N(C(C(NC([C@]([H])(C[C@@H](O)[C@@H](O)NC(C3N(C(C([C@H](O)CC(N)=O)N4)=O)C[C@H](C)[C@@H]3O)=O)NC(C5=CC=C(C6=NOC(C7=CC=C(OCCCCC)C=C7)=C6)C=C5)=O)=O)[C@H](O)C)=O)C[C@H](O)C2)=O)C4=O)=CC=C1O)(O[Na])=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Micafungin sodium (FK 463 sodium) 是抗真菌剂,抑制1, 3-beta-D-glucan的合成。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Bormann, A.M., and Morrison, V.A.Review of the pharmacology and clinical studies of micafunginDrug. Des. Devel. Ther.3,295-302(2009)

      Carillo-Muñoz, A.J., Giusiano, G., Ezkurra, P.A., et al.Antifungal agents: mode of action in yeast cellsRev.Esp.Quimioter.19(2),130-139(2006)

      Pfaller, M.A., Boyken, L., Hollis, R.J., et al.In vitro susceptibility of clinical isolates of Aspergillus spp. to anidulafungin, caspofungin, and micafungin: A head-to-head comparison using the CLSI M38-A2 broth microdilution methodJ. Clin. Microbiol.47(10),3323-3325(2009)

      Vehreschild, J.J., and Cornely, O.A.Micafungin sodium, the second of the echinocandin class of antifungals: Theory and practiceFuture Microbiol.1(2),161-170(2006)

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