Micafungin sodium
Cat. No.：YN250661
| 产品名称: | Micafungin sodium |
| CAS No.: | 208538-73-2 |
| Chemical Name: | 1-[(4R,5R)-4,5-dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-pneumocandin A0, monosodium salt |
| Synonyms: | 米卡芬净钠; FK 463 sodium |
| 分子量: | 1292.26 |
| 分子式: | C₅₆H₇₀N₉NaO₂₃S |
| SMILES: | O=S(OC1=CC([C@H](O)[C@@H](O)C(NC(C2N(C(C(NC([C@]([H])(C[C@@H](O)[C@@H](O)NC(C3N(C(C([C@H](O)CC(N)=O)N4)=O)C[C@H](C)[C@@H]3O)=O)NC(C5=CC=C(C6=NOC(C7=CC=C(OCCCCC)C=C7)=C6)C=C5)=O)=O)[C@H](O)C)=O)C[C@H](O)C2)=O)C4=O)=CC=C1O)(O[Na])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Micafungin sodium (FK 463 sodium) 是抗真菌剂，抑制1, 3-beta-D-glucan的合成。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bormann, A.M., and Morrison, V.A.Review of the pharmacology and clinical studies of micafunginDrug. Des. Devel. Ther.3,295-302(2009)
Carillo-Muñoz, A.J., Giusiano, G., Ezkurra, P.A., et al.Antifungal agents: mode of action in yeast cellsRev.Esp.Quimioter.19(2),130-139(2006)
Pfaller, M.A., Boyken, L., Hollis, R.J., et al.In vitro susceptibility of clinical isolates of Aspergillus spp. to anidulafungin, caspofungin, and micafungin: A head-to-head comparison using the CLSI M38-A2 broth microdilution methodJ. Clin. Microbiol.47(10),3323-3325(2009)
Vehreschild, J.J., and Cornely, O.A.Micafungin sodium, the second of the echinocandin class of antifungals: Theory and practiceFuture Microbiol.1(2),161-170(2006)
