Azithromycin
Cat. No.：YN250733
CAS No. ：83905-01-5
| 产品名称: | Azithromycin |
| CAS No.: | 83905-01-5 |
| Chemical Name: | (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15- |
| Synonyms: | 阿奇霉素; CP 62993 |
| 分子量: | 748.98 |
| 分子式: | C₃₈H₇₂N₂O₁₂ |
| SMILES: | C[C@@H]([C@@H]([C@@](C(O[C@@H]([C@@](C)(O)[C@@H]1O)CC)=O)([H])C)O[C@@](O[C@@H](C)[C@@H]2O)([H])C[C@@]2(C)OC)[C@H]([C@](O)(C[C@H](CN([C@@H]1C)C)C)C)O[C@@](O[C@H](C)C[C@@H]3N(C)C)([H])[C@@H]3O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Azithromycin (CP-62993) 是一种大环内酯抗生素，常用于细菌感染的研究。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Kanatani, M.S., and Guglielmo, B.J.The new macrolides. Azithromycin and clarithromycinWestern J. Med.160(1),31-37(1994)
Girard, D., Finegan, S.M., Dunne, M.W., et al.Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection modelsJ. Antimicrob. Chemother.56(2),365-371(2005)
Mostafa, A., Kandeil, A., Elshaier, Y.A.M.M., et al.FDA-approved drugs with potent in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2Pharmaceuticals (Basel)13(12),443(2020)
Patel, A., Joseph, J., Periasamy, H., et al.Azithromycin in combination with ceftriaxone reduces systemic inflammation and provides survival benefit in a murine model of polymicrobial sepsisAntimicrob. Agents Chemother.62(9),e00752-00718(2018)
