Flucytosine
Cat. No.：YN250925
CAS No. ：2022-85-7
| 产品名称: | Flucytosine |
| CAS No.: | 2022-85-7 |
| Chemical Name: | 6-amino-5-fluoro-2(1H)-pyrimidinone |
| Synonyms: | 5-氟胞嘧啶; 5-Fluorocytosine; NSC 103805; Ro 2-9915 |
| 分子量: | 129.09 |
| 分子式: | C₄H₄FN₃O |
| SMILES: | O=C1NC=C(F)C(N)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Flucytosine（5-Fluorocytosine, 5-FC, Ancobon）是抗真菌化合物。 |
| IC50和靶点: | |
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Herbrecht, R., Nivoix, Y., Fohrer, C., et al.Management of systemic fungal infections: Alternatives to itraconazoleJ. Antimicrob. Chemother.56(Suppl 1),i39-i48(2005)
Fuerer, C., and Iggo, R.5-Fluorocytosine increases the toxicity of Wnt-targeting replicating adenoviruses that express cytosine deaminase as a late geneGene Ther.11(2),142-151(2004)
Ostertag, D., Amundson, K.K., Lopez Espinoza, F., et al.Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vectorNeuro Oncol.14(2),145-159(2012)
