Ribavirin
Cat. No.：YN251040
| 产品名称: | Ribavirin |
| CAS No.: | 36791-04-5 |
| Chemical Name: | 1-β-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide |
| Synonyms: | 利巴韦林; ICN-1229 |
| 分子量: | 244.20 |
| 分子式: | C₈H₁₂N₄O₅ |
| SMILES: | O[C@H]1[C@H](N2N=C(C(N)=O)N=C2)O[C@H](CO)[C@H]1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ribavirin (ICN-1229) 是广谱的抗病毒药，可抑制HCV，HIVl，RSV等病毒。 |
| IC50和靶点: | |
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Gilbert, B.E., and Knight, V.Biochemistry and clinical applications of ribavirinAntimicrob. Agents Chemother.30(2),201-205(1986)
Gordon, C.J., Tchesnokov, E.P., Woolner, E., et al.Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potencyJ. Biol. Chem.295(20),6785-6797(2020)
Kirsi, J.J., North, J.A., McKernan, P.A., et al.Broad-spectrum antiviral activity of 2-β-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agentAntimicrob. Agents Chemother.24(3),353-361(1983)
Wang, M., Cao, R., Zhang, L., et al.Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitroCell Res.30(3),269-271(2020)
Wilson, S.Z., Knight, V., Wyde, P.R., et al.Amantadine and ribavirin aerosol treatment of influenza A and B infection in miceAntimicrob. Agents Chemother.17(4),642-648(1980)
