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Streptomycin sulfate

Cat. No.:YN251062

  • CAS No. :3810-74-0

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    • 参考文献
    • 产品名称: Streptomycin sulfate
      CAS No.: 3810-74-0
      Chemical Name: O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-D-streptamine
      Synonyms:硫酸链霉素
      分子量:728.69
      分子式:C₂₁H₄₂N₇O₁₈S₁.₅
      SMILES:O[C@@]1(C=O)[C@H]([C@@H](O[C@H]1C)O[C@]([C@@H]([C@@H](O)[C@@H]2NC(N)=N)O)([H])[C@H]([C@@H]2O)NC(N)=N)O[C@@](O[C@@H](CO)[C@H](O)[C@H]3O)([H])[C@H]3NC.[1.5H2SO4]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Streptomycin sulfate 是一种氨基糖苷类抗生素,能够抑制蛋白质的合成。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Syed, H.C., and Ravaoarinoro, M.LiF reduces MICs of antibiotics against clinical isolates of gram-positive and gram-negative bacteriaInt. J. Microbiol.,454065(2012)

      Jhamb, S.S., Goyal, A., and Singh, P.P.Determination of the activity of standard anti-tuberculosis drugs against intramacrophage Mycobacterium tuberculosis, in vitro: MGIT 960 as a viable alternative for BACTEC 460Braz. J. Infect. Dis.18(3),336-340(2014)

      Franzblau, S.G., Witzig, R.S., McLaughlin, J.C., et al.Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assayJ. Clin. Microbiol.36(2),362-366(1998)

      Lounis, N., Bentoucha, A., Truffot-Pernot, C., et al.Effectiveness of once-weekly rifapentine and moxifloxacin regimens against Mycobacterium tuberculosis in miceAntimicrob. Agents Chemother.45(12),3482-3486(2001)

      Luzzatto, L., Apirion, D., and Schlessinger, D.Mechanism of action of streptomycin in E. coli: Interruption of the ribosome cycle at the initiation of protein synthesisProc. Natl. Acad. Sci. USA60(3),873-880(1968)

      Moazed, D., and Noller, H.F.Interaction of antibiotics with functional sites in 16S ribosomal RNANature327(6121),389-394(1987)

      Carter, A.P., Clemons, W.M., Brodersen, D.E., et al.Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibioticsNature407(6802),340-348(2000)

      Sharma, D., Cukras, A.R., Rogers, E.J., et al.Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosomeJ. Mol. Biol.374(4),1065-1076(2007)

      Varghese, D.S., Parween, S., Ardah, M.T., et al.Effects of aminoglycoside antibiotics on human embryonic stem cell viability during differentiation in vitroStem Cells Int.2017,2451927(2017)

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