Puromycin dihydrochloride
Cat. No.:YN251351
CAS No. :58-58-2
产品名称: | Puromycin dihydrochloride |
CAS No.: | 58-58-2 |
Chemical Name: | 3'-[[2S-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine, dihydrochloride |
Synonyms: | 嘌呤霉素二盐酸盐; CL13900 dihydrochloride |
分子量: | 544.43 |
分子式: | C₂₂H₃₁Cl₂N₇O₅ |
SMILES: | OC[C@@H]1[C@@H](NC([C@@H](N)CC2=CC=C(OC)C=C2)=O)[C@H]([C@H](N3C=NC4=C3N=CN=C4N(C)C)O1)O.[H]Cl.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Puromycin dihydrochloride (CL13900 dihydrochloride) 是一种氨基核苷类抗生素,抑制蛋白合成 (protein synthesis)。 |
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Azzam, M.E., and Algranati, I.D.Mechanism of puromycin action: Fate of ribosomes after release of nascent protein chains from polysomesProc. Natl. Acad. Sci. USA70(12),3866-3869(1973)
Rodriguez-Fonseca, C., Phan, H., Long, K.S., et al.Puromycin-rRNA interaction sites at the peptidyl transferase centerRNA6(5),744-754(2000)
Lührmann, R., Bald, R., Stöffler-Meilicke, M., et al.Localization of the puromycin binding site on the large ribosomal subunit of Escherichia coli by immunoelectron microscopyProc. Natl. Acad. Sci. USA78(12),7276-7280(1981)