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Puromycin dihydrochloride

Cat. No.:YN251351

  • CAS No. :58-58-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Puromycin dihydrochloride
      CAS No.: 58-58-2
      Chemical Name: 3'-[[2S-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine, dihydrochloride
      Synonyms:嘌呤霉素二盐酸盐; CL13900 dihydrochloride
      分子量:544.43
      分子式:C₂₂H₃₁Cl₂N₇O₅
      SMILES:OC[C@@H]1[C@@H](NC([C@@H](N)CC2=CC=C(OC)C=C2)=O)[C@H]([C@H](N3C=NC4=C3N=CN=C4N(C)C)O1)O.[H]Cl.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Puromycin dihydrochloride (CL13900 dihydrochloride) 是一种氨基核苷类抗生素,抑制蛋白合成 (protein synthesis)。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Azzam, M.E., and Algranati, I.D.Mechanism of puromycin action: Fate of ribosomes after release of nascent protein chains from polysomesProc. Natl. Acad. Sci. USA70(12),3866-3869(1973)

      Rodriguez-Fonseca, C., Phan, H., Long, K.S., et al.Puromycin-rRNA interaction sites at the peptidyl transferase centerRNA6(5),744-754(2000)

      Lührmann, R., Bald, R., Stöffler-Meilicke, M., et al.Localization of the puromycin binding site on the large ribosomal subunit of Escherichia coli by immunoelectron microscopyProc. Natl. Acad. Sci. USA78(12),7276-7280(1981)

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