Amrubicin
Cat. No.:YN251993
产品名称: | Amrubicin |
CAS No.: | 110267-81-7 |
Chemical Name: | (7S,9S)-9-Acetyl-9-amino-7-[(2-deoxy-?-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione; |
Synonyms: | 氨柔比星; SM-5887 |
分子量: | 483.4 |
分子式: | C25H25NO9 |
SMILES: | CC([C@@](C1)(N)C[C@H](O[C@@H]2OC[C@@H](O)[C@@H](O)C2)C(C1=C3O)=C(O)C4=C3C(C5=CC=CC=C5C4=O)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Amrubicin (SM-5887) 是一种 DNA 拓扑异构酶 II (topoisomeraseII) 抑制剂,可用于癌症研究。 |
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Igarashi, J., et al.: Bioorg. Med. Chem Lett., 5, 2923 (1995), Hanada, M., et al.: Jpn. J. Cancer Res., 89, 1229 (1998), Ohe, Y., et al.: Ann. Oncol., 16, 430 (2005), Matsunaga, Y., et al.: Ther. Drug Monit., 28, 76 (2006),