BI 653048 phosphate
Cat. No.：YN252006
| 产品名称: | BI 653048 phosphate |
| CAS No.: | 1198784-97-2 |
| Chemical Name: | |
| Synonyms: | BI653048;BI 653048 |
| 分子量: | 613.517 |
| 分子式: | C23H28F4N3O8PS |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BI 653048 phosphate 是一种选择性且口服的非甾体类糖皮质激素 (glucocorticoid (GC)) 激动剂，其IC50值为 55 nM。 BI 653048 phosphate 抑制 CP1A2，CYP2D6，CYP2C9，CYP2C19 和 CYP3A4 的活性并降低对 hERG 离子通道的亲和力 (IC50>30 μM)。BI 653048 phosphate 源于专利 WO2005028501A1 (化合物 103)，它也是一种HCVNS3 protease抑制剂，可以减少感 |
| IC50和靶点: | [{name:"CYP1A2:50 μM (IC50)"},{name: "CYP2D6:41 μM (IC50)"},{name: "CYP2C9:12 μM (IC50)"},{name: "CYP2C19:9 μM (IC50)"},{name: "CYP3A4:8 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
