Cabamiquine
Cat. No.:YN252057
| 产品名称: | Cabamiquine |
| CAS No.: | 1469439-69-7 |
| Chemical Name: | |
| Synonyms: | DDD107498; DDD-498; M5717 |
| 分子量: | 462.56 |
| 分子式: | C27H31FN4O2 |
| SMILES: | C1CCN(C1)CCNC(=O)C2=CC(=NC3=C2C=C(C=C3)F)C4=CC=C(C=C4)CN5CCOCC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cabamiquine (DDD107498) 是一种有效、可口服的抗疟疾 (antimalarial) 剂,能够抑制寄生虫生命周期的多个阶段,对P. falciparum3D7 的EC50值为 1 nM。Cabamiquine 通过靶作用于eEF2/CaMKIII来抑制蛋白合成,对 WT-PfeEF2 的EC50值为 2 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |