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Derquantel

Cat. No.:YN252091

  • CAS No. :187865-22-1

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    • 参考文献
    • 产品名称: Derquantel
      CAS No.: 187865-22-1
      Chemical Name: (1'R,5'aS,7'R,8'aS,9'aR)-2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one
      Synonyms:PF-00520904
      分子量:479.6
      分子式:C28H37N3O4
      SMILES:CC(C=CO1)(C)OC2=C1C(NC3)=C(C=C2)[C@]3(C4(C)C)C[C@]5(N(C)C6=O)[C@@]4([H])C[C@]6([C@](C)(O)CC7)N7C5
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Derquantel 是一种有效的驱虫药。Derquantel 会引起线虫的松驰性麻痹和排出。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Holden-Dye, L., and Walker, R.J.Anthelmintic drugs and nematicides: Studies in Caenorhabditis elegansWormBook16,1-29(2014)

      Abongwa, M., Buxton, S.K., Robertson, A.P., et al.Curiouser and curiouser: The macrocyclic lactone, abamectin, is also a potent inhibitor of pyrantel/tribendimidine nicotinic acetylcholine receptors of gastro-intestinal wormsPLoS One11(1),(2016)

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