Guanabenz hydrochloride
Cat. No.：YN252123
CAS No. ：23113-43-1
| 产品名称: | Guanabenz hydrochloride |
| CAS No.: | 23113-43-1 |
| Chemical Name: | 2-[(2,6-dichlorophenyl)methylene]-hydrazinecarboximidamide, monohydrochloride |
| Synonyms: | |
| 分子量: | 267.5 |
| 分子式: | C8H8Cl2N4 • HCl |
| SMILES: | ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Guanabenz hydrochloride 是一种 α-2 肾上腺素受体激动剂，具有口服活性。Guanabenz hydrochloride 具有抗高血压和抗寄生虫活性。Guanabenz hydrochloride 干扰内质网应激信号传导，对心肌细胞具有保护作用。Guanabenz hydrochloride 也被用于高血压的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Sakakibara, Y., Muramatsu, I., Fujiwara, M., et al.Effects of guanabenz on the adrenergic mechanism in rabbit arterial stripsJpn. J. Pharmacol.31(6),1029-1036(1981)
Sica, D.A.Centrally acting antihypertensive agents: An updateJ. Clin. Hypertens. (Greenwich)9(5),399-405(2007)
Römer, L., Wurster, S., Savola, J.M., et al.Identification and characterization of the imidazoline I2b-binding sites in the hamster brown adipose tissue as a study model for imidazoline receptorsArch. Physiol. Biochem.111(2),159-166(2003)
