Pyocyanin
Cat. No.：YN252246
CAS No. ：85-66-5
| 产品名称: | Pyocyanin |
| CAS No.: | 85-66-5 |
| Chemical Name: | 5-methyl-1(5H)-phenazinone |
| Synonyms: | Pyocyanine; Sanazin; Sanasin |
| 分子量: | 210.2 |
| 分子式: | C13H10N2O |
| SMILES: | Cn1c2ccccc2nc2c(=O)cccc12 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pyocyanin (Pyocyanine) 是一种由铜绿假单胞菌产生的有毒、群体感应 (QS) 控制的代谢物。Pyocyanin 是一种氧化还原活性化合物，可促进活性氧 (ROS) 产生。Pyocyanin还具有抗菌特性，并增加与其他细菌物种竞争的适应性。 |
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Moura-Alves, P., Faé, K., Houthuys, E., et al.AhR sensing of bacterial pigments regulates antibacterial defenceNature512(7515),387-392(2014)
Allen, L., Dockrell, D.H., Pattery, T., et al.Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivoJ. Immunol.174,3643-3649(2005)
Muller, M.Premature cellular senescence induced by pyocyanin, a redox-active Pseudomonas aeruginosa toxinFree Radic. Biol. Med.41,1670-1677(2006)
Muller, M.Pyocyanin induces oxidative stress in human endothelial cells and modulates the glutathione redox cycleFree Radic. Biol. Med.33(11),1527-1533(2002)
