Grazoprevir hydrate
Cat. No.：YN252348
CAS No. ：1350462-55-3
| 产品名称: | Grazoprevir hydrate |
| CAS No.: | 1350462-55-3 |
| Chemical Name: | |
| Synonyms: | 阿那匹韦; MK-5172 hydrate |
| 分子量: | 784.92 |
| 分子式: | C38H52N6O10S |
| SMILES: | COC1=CC2=C(N=C(CCCCC[C@@H]3C[C@H]3OC4=O)C(O[C@H]5CN(C([C@H](C(C)(C)C)N4)=O)[C@H](C(N[C@@]([C@@H]6C=C)(C6)C(NS(C7CC7)(=O)=O)=O)=O)C5)=N2)C=C1.O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Grazoprevir hydrate (MK-5172 hydrate) 是选择性的丙型肝炎病毒 NS3/4a蛋白酶抑制剂，作用于 gt1b，gt1a，gt2a，gt2b 和 gt3a的Ki分别为 0.01 nM，0.01 nM，0.08 nM，0.15 nM 和 0.90 nM。Grazoprevir hydrate 抑制 SARS-CoV-2 3CLpro活性。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
