Elbasvir

Cat. No.：1370468-36-2

CAS No. ：1370468-36-2

产品名称:	Elbasvir
CAS No.:	1370468-36-2
Chemical Name:
Synonyms:	MK-8742
分子量:	882.02
分子式:	C₄₉H₅₅N₉O₇
SMILES:	O=C([C@H](C(C)C)NC(OC)=O)N(CCC1)[C@@H]1C(N2)=NC=C2C(C=C3)=CC4=C3C5=CC6=CC(C7=CN=C([C@H]8N(C([C@H](C(C)C)NC(OC)=O)=O)CCC8)N7)=CC=C6N5[C@H](C9=CC=CC=C9)O4
存储:	Please store the product under the recommended conditions in theCertificate of Analysis.
运输:	Room temperature in continental US; may vary elsewhere.

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Purity: 0.98

Lahser, F.C., Bystol, K., Curry, S., et al.The combination of grazoprevir, a Hepatitis C virus (HCV) NS3/4A protease inhibitor, and elbasvir, an HCV NS5A inhibitor, demonstrates a high genetic barrier to resistance in HCV genotype 1a repliconsAntimicrob. Agents Chemother.60(5),2954-2964(2016)', 'McGivern, D.R., Masaki, T., Williford, S., et al.Kinetic analyses reveal potent and early blockade of hepatitis C virus assembly by NS5A inhibitorsGastroenterology147(2),453-462(2014)', 'Asante-Appiah, E., Curry, S., McMonagle, P., et al.Antiviral activity and resistance analysis of NS3/4A protease inhibitor grazoprevir and NS5A inhibitor elbasvir in Hepatitis C virus GT4 repliconsAntimicrob. Agents Chemother.61(7),e00363-e00417(2017)', 'Liu, R., Curry, S., McMonagle, P., et al.Susceptibilities of genotype 1a, 1b, and 3 hepatitis C virus variants to the NS5A inhibitor elbasvirAntimicrob. Agents Chemother.59(11),6922-6929(2015)