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Voreloxin

Cat. No.：175414-77-4

  • CAS No. ：175414-77-4

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    • 产品名称: Voreloxin
      CAS No.: 175414-77-4
      Chemical Name:
      Synonyms:SNS-595; Vosaroxin; AG 7352
      分子量:401.44
      分子式:C₁₈H₁₉N₅O₄S
      SMILES:O=C(C1=CN(C2=NC=CS2)C3=C(C=CC(N4C[C@H](OC)[C@@H](NC)C4)=N3)C1=O)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Tsuzuki, Y., Tomita, K., Shibamori, K.-i., et al.Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 2J. Med. Chem.47(8),2097-2109(2004)', 'Hawtin, R.E., Stockett, D.E., Byl, J.A.W., et al.Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase IIPLoS One5(4),e10186(2010)', 'Hoch, U., Lynch, J., Sato, Y., et al.Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor modelsCancer Chemother. Pharmacol.64(1),53-65(2009)
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