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Mocetinostat

Cat. No.：726169-73-9

  • CAS No. ：726169-73-9

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    • 产品名称: Mocetinostat
      CAS No.: 726169-73-9
      Chemical Name:
      Synonyms:MGCD0103
      分子量:396.44
      分子式:C₂₃H₂₀N₆O
      SMILES:O=C(C1=CC=C(C=C1)CNC2=NC=CC(C3=CC=CN=C3)=N2)NC4=CC=CC=C4N
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Fournel, M., Bonfils, C., Hou, Y., et al.MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivoMol. Cancer Ther.7(4),759-768(2008)', 'Marson, C.M., Matthews, C.J., Atkinson, S.J., et al.Potent and selective inhibitors of histone deacetylase-3 containing chiral oxazoline capping groups and a N-(2-aminophenyl)-benzamide binding unitJ. Med. Chem.58(17),6803-6818(2015)', 'Bonfils, C., Kalita, A., Dubay, M., et al.Evaluation of the pharmacodynamic effects of MGCD0103 from preclinical models to human using a novel HDAC enzyme assayClin. Cancer Res.14(11),3441-3449(2008)', 'Nural-Guvener, H., Zakharova, L., Feehery, L., et al.Anti-fibrotic effects of class I HDAC inhibitor, mocetinostat is associated with IL-6/Stat3 signaling in ischemic heart failureInt. J. Mol. Sci.16(5),11482-11499(2015)
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