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β-Lapachone

Cat. No.：4707-32-8

  • CAS No. ：4707-32-8

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    • 产品名称: β-Lapachone
      CAS No.: 4707-32-8
      Chemical Name:
      Synonyms:ARQ-501; NSC-26326
      分子量:242.27
      分子式:C₁₅H₁₄O₃
      SMILES:O=C(C1=C2OC(C)(C)CC1)C(C3=C2C=CC=C3)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Li, C.J., Averboukh, L., and Pardee, A.B.β-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecinJ. Biol. Chem.268(30),22463-22468(1993)', 'Lai, T.-S., Liu, Y., Tucker, T., et al.Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug librariesChem. Biol.15(9),969-978(2008)', 'Siegel, D., Yan, C., and Ross, D.NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinonesBiochem. Pharmacol.83(8),1033-1040(2012)', 'Dong, G.Z., Oh, E.T., Lee, H., et al.β-Lapachone suppresses radiation-induced activation of nuclear factor-κBExp. Mol. Med.42(5),327-334(2010)', 'Li, L.S., Bey, E.A., Dong, Y., et al.Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapyClin. Cancer Res.17,275-285(2011)
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