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Cladribine

Cat. No.：4291-63-8

  • CAS No. ：4291-63-8

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    • 产品名称: Cladribine
      CAS No.: 4291-63-8
      Chemical Name:
      Synonyms:克拉屈滨; 2-Chloro-2′-deoxyadenosine; CldAdo; 2CdA
      分子量:285.69
      分子式:C₁₀H₁₂ClN₅O₃
      SMILES:OC[C@@H]1[C@H](C[C@H](N2C=NC3=C2N=C(Cl)N=C3N)O1)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Hermann, R., Krajcsi, P., Fluck, M., et al.Cladribine as a potential object of nucleoside transporter‑based drug interactionsClin. Pharmacokinet.,(2021)', 'Carson, D.A., Wasson, D.B., Taetle, R., et al.Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytesBlood62(4),737-743(1983)', 'Seto, S., Carrera, C.J., Kubota, M., et al.Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytesJ. Clin. Invest.75(2),377-383(1985)', 'Ma, J., Wang, S., Zhao, M., et al.Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myelomaBMC Cancer11,255(2011)', 'Bagley, R.G., Roth, S., Kurtzberg, L.S., et al.Bone marrow CFU-GM and human tumor xenograft efficacy of three antitumor nucleoside analogsInt. J. Oncol.34(5),1329-1340(2009)
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