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GSK2656157

Cat. No.：1337532-29-2

  • CAS No. ：1337532-29-2

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    • 产品名称: GSK2656157
      CAS No.: 1337532-29-2
      Chemical Name:
      Synonyms:
      分子量:416.45
      分子式:C₂₃H₂₁FN₆O
      SMILES:CC1=CC=CC(CC(N2CCC3=C2C=CC(C4=CN(C)C5=NC=NC(N)=C54)=C3F)=O)=N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Atkins, C., Liu, Q., Minthorn, E., et al.Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activityCancer Res.73(6),1993-2002(2013)', 'Axten, J.M., Romeril, S.P., Shu, A., et al.Discovery of GSK2656157: An optimized PERK inhibitor selected for preclinical developmentACS Med. Chem. Lett.4,964-968(2013)', 'Ando, T., Komatsu, T., Naiki, Y., et al.GSK2656157, a PERK inhibitor, reduced LPIS-induced IL-1b production through inhibiting caspase 1 activation in macrophage-like J774.1 cellsImmunopharmacol. Immunotoxicol.38(4),298-302(2016)
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