F16
Cat. No.：YN270006
CAS No. ：36098-33-6
| 产品名称: | F16 |
| CAS No.: | 36098-33-6 |
| Chemical Name: | 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-pyridinium iodide |
| Synonyms: | (E)-4-(3-indolylvinyl)-N-methylpyridinium iodide |
| 分子量: | 362.21 |
| 分子式: | C₁₆H₁₅IN₂ |
| SMILES: | C[N+]1=CC=C(/C=C/C2=CNC3=C2C=CC=C3)C=C1.[I-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | F16 是neu过表达细胞的有效生长抑制剂，还可以选择性抑制乳腺上皮以及多种小鼠乳腺肿瘤和人乳腺癌细胞系的增殖。F16 是线粒体毒性化合物，根据靶癌细胞的遗传背景触发凋亡或坏死。 |
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| Solvent & Solubility: |
Fantin, V.R., Berardi, M.J., Scorrano, L., et al.A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growthCancer Cell2(1),29-42(2002)
