INH6
Cat. No.：YN270010
CAS No. ：1001753-24-7
| 产品名称: | INH6 |
| CAS No.: | 1001753-24-7 |
| Chemical Name: | N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-benzamide |
| Synonyms: | N-(4-mesitylthiazol-2-yl)benzamide;INH6;N-[4-(2,4,6-trimethylphenyl)thiazol-2-yl]benzamide;N-[4-(2,4,6-trimethylphenyl)-2-thiazolyl]-benzamide;N-[4-(2,4,6-trimethylphenyl)-1,3-thiazol-2-yl]benzamide;C19H18N2OS;N-(4-(2,4,6-trimethylphenyl)thiazol-2-yl)benz |
| 分子量: | 322.42 |
| 分子式: | C₁₉H₁₈N₂OS |
| SMILES: | O=C(NC1=NC(C2=C(C)C=C(C)C=C2C)=CS1)C3=CC=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | INH6是有效的Nek2/Hec1抑制剂；抑制HeLa细胞生长的IC50值为2.4 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Qiu, X.-L., Li, G., Wu, G., et al.Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analoguesJ. Med. Chem.52(6),1757-1767(2009)
Lee, Y.-S., Chuang, S.-H., Huang, L.Y., et al.Discovery of 4-aryl-N-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 inhibitors. Part I: Optimization of in vitro potencies and pharmacokinetic propertiesJ. Med. Chem.57(10),4098-4110(2014)
