Kinetin riboside
Cat. No.:YN270025
CAS No. :4338-47-0
产品名称: | Kinetin riboside |
CAS No.: | 4338-47-0 |
Chemical Name: | N-(2-furanylmethyl)-adenosine |
Synonyms: | N6-Furfuryladenosine |
分子量: | 347.33 |
分子式: | C₁₅H₁₇N₅O₅ |
SMILES: | OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NCC4=CC=CO4)O1)O)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Kinetin riboside是细胞分裂素类似物,可诱导癌症细胞死亡。抑制HCT-15细胞增殖的IC50值为2.5 μM。 |
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Orlicka-Płocka, M., Gurda-Wozna, D., Fedoruk-Wyszomirska, A., et al.Circumventing the Crabtree effect: Forcing oxidative phosphorylation (OXPHOS) via galactose medium increases sensitivity of HepG2 cells to the purine derivative kinetin ribosideApoptosis25(11-12),835-852(2020)
Tiedemann, R.E., Mao, X., Shi, C.-X., et al.Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activityJ. Clin. Invest.118(5),1750-1764(2008)