Tubastatin A Hydrochloride
Cat. No.：YN270220
CAS No. ：1310693-92-5
| 产品名称: | Tubastatin A Hydrochloride |
| CAS No.: | 1310693-92-5 |
| Chemical Name: | N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide Hydrochloride |
| Synonyms: | Tubastatin A HCl; TSA HCl |
| 分子量: | 371.86 |
| 分子式: | C₂₀H₂₂ClN₃O₂ |
| SMILES: | O=C(C1=CC=C(C=C1)CN2C3=C(C4=C2C=CC=C4)CN(C)CC3)NO.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tubastatin A Hydrochloride 是一种有效的，选择性的HDAC6抑制剂，IC50值为 15 nM，对其选择性是 HDAC8 外的其他亚型的 1000 多倍。 |
| IC50和靶点: | [{name:"HDAC6:15 nM (IC50)"},{name: "HDAC8:854 nM (IC50)"},{name: "HDAC1:16400 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Cenik, B., et al.: J. Biol. Chem., 286, 16101 (2011)
