Bendamustine
Cat. No.:YN270238
CAS No. :16506-27-7
产品名称: | Bendamustine |
CAS No.: | 16506-27-7 |
Chemical Name: | 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid; 4-[5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic Acid; ω-[1-Methyl-5-[bis(β-chloroethyl)amino]-2-benzimidazolyl]butyric Acid; |
Synonyms: | SDX-105 free base |
分子量: | 358.26 |
分子式: | C₁₆H₂₁Cl₂N₃O₂ |
SMILES: | O=C(O)CCCC1=NC2=CC(N(CCCl)CCCl)=CC=C2N1C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Bendamustine (SDX-105 free base),一种嘌呤类似物,是一种DNA交联剂。Bendamustine 可激活 DNA 损伤反应和细胞凋亡 (apoptosis)。Bendamustine 具有有效的烷基化,抗癌和抗代谢作用。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996)
Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001)