Epirubicin hydrochloride
Cat. No.：YN270246
CAS No. ：56390-09-1
| 产品名称: | Epirubicin hydrochloride |
| CAS No.: | 56390-09-1 |
| Chemical Name: | (8S,10S)-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione, monohydrochloride |
| Synonyms: | 盐酸表柔比星; 4'-Epidoxorubicin hydrochloride |
| 分子量: | 579.98 |
| 分子式: | C₂₇H₃₀ClNO₁₁ |
| SMILES: | O=C(C1=C2C(O)=C3[C@@H](O[C@@]4([H])C[C@H](N)[C@@H](O)[C@H](C)O4)C[C@@](C(CO)=O)(O)CC3=C1O)C5=CC=CC(OC)=C5C2=O.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride) 是阿霉素的半合成的 L-阿拉伯糖衍生物，能够抑制Topoisomerase，起到抗肿瘤的作用。Epirubicin hydrochloride 是一种 Forkhead box 蛋白 p3 (Foxp3) 抑制剂，可抑制调节性 T 细胞活性。 |
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Arcamone, F.Properties of antitumor anthracyclines and new developments in their application: Cain memorial award lectureCancer Res.45(12 Pt 1),5995-5999(1985)
Yao, X., Hosenpud, J., Chitambar, C.R., et al.A phase II study of concurrent docetaxel, epirubicin and cyclophospha-mide as a neoadjuvant chemotherapy regimen in patients with locally advanced breast cancerJ. Cancer3,145-151(2012)
