Pemetrexed disodium hemipenta hydrate
Cat. No.：YN270267
| 产品名称: | Pemetrexed disodium hemipenta hydrate |
| CAS No.: | 357166-30-4 |
| Chemical Name: | |
| Synonyms: | 培美曲塞二钠水合物; LY231514 disodium hemipenta hydrate |
| 分子量: | 516.41 |
| 分子式: | C₂₀H₂₄N₅Na₂O₈.₅ |
| SMILES: | O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(CCC2=CNC(N=C(N)N3)=C2C3=O)C=C1)=O.[2.5H2O] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pemetrexed disodium hemipenta hydrate 是一种叶酸拮抗剂 (antifolate)。抑制胸苷酸合成酶 (TS)，二氢叶酸还原酶 (DHFR) 和甘氨酰胺核苷酸甲酰转移酶 (GARFT)，Ki分别为 1.3 nM，7.2 nM 和 65 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
