INH1
Cat. No.：YN270347
CAS No. ：313553-47-8
| 产品名称: | INH1 |
| CAS No.: | 313553-47-8 |
| Chemical Name: | N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-benzamide |
| Synonyms: | IBT13131 |
| 分子量: | 308.40 |
| 分子式: | C₁₈H₁₆N₂OS |
| SMILES: | O=C(NC1=NC(C2=CC=C(C)C=C2C)=CS1)C3=CC=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | INH1 通过直接结合Hec1，特异性干扰 Hec1/Nek2 的相互作用。INH1 在体内和体外均表现出良好的抗肿瘤活性。 |
| IC50和靶点: | |
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Wu, G., Qiu, X.-L., Zhou, L., et al.Small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animalCancer Res.68(20),8393-8399(2008)
Zheng, S., Zhong, Q., Jiang, Q., et al.Discovery of a series of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasionACS Med. Chem. Lett.4(2),191-196(2013)
