Bioymifi
Cat. No.：YN270367
CAS No. ：1420071-30-2
规格
价格(RMB)
库存
| 产品名称: | Bioymifi |
| CAS No.: | 1420071-30-2 |
| Chemical Name: | 5-[5-[[3-(4-bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-1H-isoindole-1,3(2H)-dione |
| Synonyms: | DR5 Activator |
| 分子量: | 494.32 |
| 分子式: | C₂₂H₁₂BrN₃O₄S |
| SMILES: | O=C(/C(SC1=N)=C/C2=CC=C(O2)C3=CC(C(N4)=O)=C(C=C3)C4=O)N1C5=CC=C(C=C5)Br |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bioymifi 是一种有效的 TRAIL 受体DR5激活剂，与DR5的胞外结构域 (ECD) 结合，Kd为 1.2 μM，Bioymifi 可作为单一的诱导剂诱导 DR5 的聚集，导致细胞凋亡。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Wang, G., Wang, X., Yu, H., et al.Small-molecule activation of the TRAIL receptor DR5 in human cancer cellsNat. Chem. Biol.9,84-90(2012)
