PRIMA-1
Cat. No.：YN270399
CAS No. ：5608-24-2
| 产品名称: | PRIMA-1 |
| CAS No.: | 5608-24-2 |
| Chemical Name: | 2,2-bis(hydroxymethyl)-3-quinuclidinone |
| Synonyms: | NSC-281668 |
| 分子量: | 185.22 |
| 分子式: | C₉H₁₅NO₃ |
| SMILES: | O=C1C(CO)(CO)N2CCC1CC2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PRIMA-1 (NSC-281668) 是一种突变型p53复活剂，可恢复 TP53 突变型甲状腺癌细胞对组蛋白甲基化抑制剂 3-Deazaneplanocin A 的敏感性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Bykov, V.J.N., Issaeva, N., Shilov, A., et al.Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compoundNat. Med.8(3),282-288(2002)
